Circulating Specialized Proresolving Lipid Mediators after Short-term EPA/DHA-Supplementation
This article at a glance
- This study addressed the levels of anti-inflammatory and resolution-promoting lipid mediators derived from EPA and DHA in human plasma during oral supplementation with EPA/DHA over a relatively short period of five days.
- The potential effect of aspirin on the selective formation of stereoisomers of several derivatives was also assessed.
- The results show that resolvin E1 in plasma is sensitive to supplementation, and that one of the most recently discovered resolvins, RvE3, is present in the circulation.