Evaluating PCSK9 as a New Point of Control for the Actions of Omega-3 LCPUFA on Blood Lipids
This article at a glance
- Two recent studies have addressed if dietary supplementation with fish oil or DHA-enriched canola oil would modify the plasma levels of PCSK9, a pivotal regulator of LDL levels.
- Modest decreases in PCSK9 levels were achieved in both studies, demonstrating that this protein is susceptible to dietary intervention by omega-3 LCPUFA.
- New studies may assess if PCSK9 down-regulation by omega-3 LCPUFA supplementation is of benefit to people with elevated LDL levels.