Evaluating the Formation of Non-Enzymatic Oxidation Products of EPA and AA in a Population at Risk for Omega-3 Long-Chain Polyunsaturated Fatty Acid Deficiency
This article at a glance
- This study addressed the relationship between omega-3 status in the Inuit and the plasma levels of omega-3 LCPUFA-derived isoprostanes.
- EPA-derived isoprostane levels were positively related to omega-3 fatty acid status, and unrelated to cardiometabolic risk factors, unlike isoprostanes derived from arachidonic acid.
- Older Inuit that adhere more strongly to traditional marine food sources had higher levels of EPA-derived isoprostanes, possibly reflecting a contribution of higher omega-3 intake to reducing cardiometabolic disease risk.