Research Summary Archives
Prenatal & Infant Health
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Perinatal Omega-3 Deficiency May Condition Future Sensitivity to Food Reward and Impaired Energy Expenditure
Posted by pufa | December 22, 2017This article at a glance Is it possible that the quality of food during gestation and around birth sets the stage for the eating behaviour of the offspring when they become adults? This study reports that in mice a perinatal deficiency in dietary omega-3 fatty acids has long-lasting effects int...
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Maternal Plasma Docosahexaenoic Acid (DHA) Concentrations Increase at the Critical Time of Neural Tube Closure
Posted by pufa | April 15, 2017Barbara J Meyer (University of Wollongong, Australia) Dilys J Freeman (University of Glasgow, UK) Docosahexaenoic acid (DHA) and polyunsaturated fatty acid (PUFA) metabolism DHA is an omega-3 long chain polyunsaturated fatty acid (n-3 LCPUFA) containing 22 carbons and 6 carbon to ca...
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Bronchopulmonary Dysplasia in Preterm Infants – Understanding the Physiological Changes in AA and DHA during Gestation
Posted by pufa | March 01, 2017This article at a glance Bronchopulmonary dysplasia is a form of lung injury caused by assisted ventilation and oxygen support compounding an incomplete development of lung tissue observed in very early and low birth weight preterm infants. In a study of fetal fatty acid (LCPUFA) accretion duri...
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Is Arachidonic Acid Required to Balance Docosahexaenoic Acid in Infant Feeding for Proper Development?
Posted by pufa | September 30, 2016Thomas Brenna Division of Nutritional Sciences Cornell University Ithaca, NY 14853 USA jtb4@cornell.edu / 607-255-9182 The long chain polyunsaturated fatty acids (LC-PUFA) docosahexaenoic acid (DHA) and arachidonic acid (AA, or ARA) are conserved components of the breast milks of all w...
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Understanding Defects in Fatty Acid Mobilization to Safeguard Fetal DHA Accretion in Gestational Diabetes
Posted by pufa | April 29, 2016This article at a glance This study documented the changes in circulating levels of various fatty acids during the third trimester of pregnancy complicated by gestational diabetes. In gestational diabetes, defects in the mobilization of several fatty acids were identified, including the DHA nec...
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Achieving Seizure Freedom with Fish Oil in Children with Treatment-Resistant Epilepsy
Posted by pufa | December 17, 2015This article at a glance This study addressed the question whether daily intake of fish oil during three months had an effect on treatment-resistant epilepsy in children. More than half of the children had no epileptic attacks during the intervention period. The results support a limited numb...
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Enhanced Production of Breast Milk DHA during Chia Oil Intake
Posted by pufa | December 17, 2015This article at a glance A randomized controlled intervention trial has addressed the effect of chia oil intake during pregnancy and nursing on breast milk fatty acid composition in healthy women. In addition to increased levels of alpha-linolenic acid, a marked elevation in docosahexaenoic ...
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Evidence for Sexual Dimorphism in the Neonatal Fat Mass Response to Maternal Long-Chain PUFA Intake
Posted by pufa | August 29, 2015This article at a glance Omega-3 long-chain polyunsaturated fatty acid (LCPUFA) intake during pregnancy has been associated with a small but significant increase in the average length of a healthy pregnancy, as well as the body weight of a newborn. In this study the investigators address the se...
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Advances in Understanding the Relationship between Child Problem Behavior and Maternal Long-Chain PUFA Intake
Posted by pufa | August 28, 2015This article at a glance An important area in omega-3 research addresses the possibility to prevent or alleviate ADHD in childhood by omega-3 supplementaton with omega-3 LCPUFA of mothers during pregnancy or the children with ADHD themselves. A higher n-3:n-6 ratio during mid-pregnancy was foun...
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Assessing the Effectiveness of Omega-3 Long-Chain Polyunsaturated Fatty Acids in Environmental Enteropathy in Children
Posted by pufa | April 29, 2015This article at a glance Environmental enteropathy is increasingly being recognized to contribute to nutrient malabsorption and augmented catabolism in young children living in conditions where fecal to oral contamination occurs constantly. Besides improving sanitary conditions, no effective me...
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Increased Length of Gestation Linked with Self-reported Omega-3 Use during Pregnancy in Women at High Risk due to Psychiatric and Psychotropic Use
Posted by pufa | April 29, 2015This article at a glance In this report the authors demonstrate that omega-3 fatty acids should be researched further as a variable to decrease obstetrical risk in women with psychiatric disorders Further research is needed as the data is consistent with the existing literature that omega-3 fat...
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Should Infant Formula Provide Only DHA, or DHA along with Arachidonic Acid?
Posted by pufa | April 29, 2015Berthold Koletzko1, Susan E. Carlson2, Johannes B. van Goudoever3 1Ludwig-Maximilians-University of Munich, Dr. von Hauner Children’s Hospital, Univ. of Munich Medical Center, München, Germany 2Univ. of Kansas Medical Center, Kansas City, KS, USA 3Depts. of Paediatrics, Emma Children’s Hospital, ...