Research Summary Archives
Mental Health and Cognition
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Omega-3 LCPUFA Chemical Oxidation Pathways Associated with Cognitive Disorders
Posted by pufa | June 30, 2018This article at a glance Neuroprostanes are oxidation products of DHA that are produced endogenously via non-enzymatic pathways. The chemical structure and biological activity has only been characterized for some of the neuroprostanes.This study reports that two neuroprostanes, 4-F4t-NeuroP an...
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Gaining Control over Physical Aggression
Posted by pufa | June 30, 2018This article at a glance A recent, carefully controlled study, has investigated whether daily supplementation with EPA/DHA could attenuate physical aggression.The study reports an important reduction in the level of self-reported physical aggression. The World Health Organization defines in...
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Perinatal Omega-3 Deficiency May Condition Future Sensitivity to Food Reward and Impaired Energy Expenditure
Posted by pufa | December 22, 2017This article at a glance Is it possible that the quality of food during gestation and around birth sets the stage for the eating behaviour of the offspring when they become adults? This study reports that in mice a perinatal deficiency in dietary omega-3 fatty acids has long-lasting effects int...
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DHA - Are Memories Made of This?
Posted by pufa | December 22, 2017This article at a glance The hippocampal-prefrontal cortex (H-PFC) pathway is a neuronal circuit that is central to integrating working memory with contextual information, facilitating executive function, such as making decisions. A recent neuroscience study in the rat reports that enzymatic co...
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Failure to Replicate Findings on Omega-3 LCPUFA Supplementation on the Transition to Psychotic Disorder in Individuals at Ultra-High Risk
Posted by pufa | March 01, 2017This article at a glance Psychotic disorders encompass serious psychiatric disorders, manifesting themselves in the altered perception of reality, such as delusions or hallucinations, disorganized or bizarre behaviors and “negative” symptoms, which include flatness of emotion and interperso...
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Omega-3 LCPUFA Status may Determine the Effectiveness of Supplemental B-Vitamin Intake in Decreasing the Rate of Cognitive Decline in Elderly People
Posted by pufa | August 29, 2015This article at a glance Alzheimer’s Disease is an accelerated form of age-related cognitive decline characterized by brain atrophy. This study has uncovered a previously unknown association between higher omega-3 LCPUFA status and the potential for inhibition by supplemental B-vitamin intak...
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Advances in Understanding the Relationship between Child Problem Behavior and Maternal Long-Chain PUFA Intake
Posted by pufa | August 28, 2015This article at a glance An important area in omega-3 research addresses the possibility to prevent or alleviate ADHD in childhood by omega-3 supplementaton with omega-3 LCPUFA of mothers during pregnancy or the children with ADHD themselves. A higher n-3:n-6 ratio during mid-pregnancy was foun...
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Increased Length of Gestation Linked with Self-reported Omega-3 Use during Pregnancy in Women at High Risk due to Psychiatric and Psychotropic Use
Posted by pufa | April 29, 2015This article at a glance In this report the authors demonstrate that omega-3 fatty acids should be researched further as a variable to decrease obstetrical risk in women with psychiatric disorders Further research is needed as the data is consistent with the existing literature that omega-3 fat...
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EPA/DHA - Perspectives for Neuropsychological Improvement in Malnourished Pre-adolescent Children
Posted by pufa | August 28, 2014Malnutrition, defined by insufficient energy and protein intake, seriously affects cognitive functions. Nutritional deficiencies early in a child’s development have marked consequences for cognitive development and overall growth at later ages of development. Malnutrition is a preventable malady but...
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Addressing Depression in Maintenance Hemodialysis Patients
Posted by pufa | August 28, 2014In end-stage renal disease, over 90% of kidney function has been lost. Hemodialysis has long been a solution to prolong the life of end-stage renal disease patients. Depressive symptoms and distress are very common in chronic hemodialysis patients with end-stage renal disease, with an estimated prev...
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Attention and Working Memory of Term Infants Unrelated to Prenatal Maternal DHA-Supplementation
Posted by pufa | April 23, 2014One of the most important reasons to assure the adequate intake of long-chain omega-3 PUFAs (n-3 LC-PUFAs) during pregnancy and early infancy is the importance of these fatty acids, especially DHA, in the structural and functional development of the brain. Although DHA is found in cell membranes thr...
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EPA Significantly Reduces Depressive Episodes in Interferon-Alpha-Treated Hepatitis C Patients
Posted by pufa | April 23, 2014Interferons are a class of cytokines with important immunoregulatory properties, including antiviral and anticarcinogenic effects. They are especially important in the body’s innate immune response to viral infections and are widely used in the primary and adjunct treatment of hepatitis B and C viru...