Research Summary Archives

This article at a glance Is it possible that the quality of food during gestation and around birth sets the stage for the eating behaviour of the offspring when they become adults? This study reports that in mice a perinatal deficiency in dietary omega-3 fatty acids has long-lasting effects int...

This article at a glance This study addressed the potential effectiveness of daily EPA/DHA for migraine headaches in adults with chronic migraine also taking low-dose amitriptyline, a drug used for migraine prevention. Participants taking both EPA/DHA and amitriptyline for 2 months reported a m...

This article at a glance This study reports that the coagulation of blood leads to the formation of arachidonic acid (AA)-, eicosapentaenoic acid (EPA)- and docosahexaenoic acid (DHA)-derived specialized proresolving mediators (SPMs) that promote microbial clearance. Clotting of human whole blo...

This article at a glance The influence on tissue fatty acid composition of three different isocaloric diets  containing carbohydrates with a low glycemic index, carbohydrates with a high glycemic index, or a reduced fat content, respectively, was assessed in overweight-obese adults on a 500 kcal/...

This article at a glance This study identifies the omega-3 polyunsaturated fatty acid hexadecatetraenoic acid (16:4 n-3) as a ligand of GPR120, a receptor studied for its role in regulating inflammation, energy metabolism and satiety. 16:4 n-3, previously identified as a fatty acid released ...

This article at a glance This pilot study evaluated the concept that stratification of study participants can be useful for improving interpretations of the relationship between long-chain polyunsaturated fatty acid (LCPUFA) intake and biological effect. In patients scheduled for coronary ar...

This article at a glance The effects of omega-3 long-chain polyunsaturated fatty acids (LCPUFA) on deranged glucose homeostasis in type 2 diabetics are incompletely understood. Metabolomic analyses of blood samples from two recent randomized controlled clinical trials in American and Chinese ad...

Jean-Marie Galano, Camille Oger, Valérie Bultel-Poncé, Guillaume Reversat, Alexandre Guy, Joseph Vercauteren, Claire Vigor, Thierry Durand. Institut des Biomolécules Max Mousseron (IBMM), UMR 5247, CNRS, Université de Montpellier, ENSCM, Montpellier, France.   Thierry Durand Institut des Bi...

Enhancing Breast Cancer Treatment with Omega-3 Fatty Acids Miranda Brun, PhD and Catherine J. Field, PhD RD Department of Agricultural, Food and Nutritional Science University of Alberta, Edmonton, Alberta, Canada   In North America and Europe, breast cancer accounts for over 25%...

This article at a glance In adults that develop colorectal cancer, survival is increased if omega-3 LCPUFA intake is modestly increased after diagnosis. Large prospective cohort studies tracked colorectal cancer incidence and assessed genomic stability and immune cell composition of tumors in r...

This article at a glance This study addressed if any associations exist between self-reported dietary intake of polyunsaturated fatty acids and obesity in 7-12 year old US American children from a racially diverse background. Associations were identified between higher total PUFA intake and low...

This article at a glance This study assessed if in a large group of patients taking low-dose aspirin for thromboprophylactic purposes during their otherwise daily life, the concurrent use of prescription omega-3 fatty acids would affect the incidence of upper-gastrointestinal complications. Dra...